疏風飲抗Ⅰ型超敏反應的實驗研究.pdf

1、遼寧中醫(yī)藥大學碩士學位論文疏風飲抗Ⅰ型超敏反應的實驗研究姓名：陳興申請學位級別：碩士專業(yè)：中西醫(yī)結合基礎指導教師：關洪全20080515ExperimentalStudyofShufengDecoctionResistingTypeIHypersensltlvltv●●●●Major：BasicDisciplineofChineseandWesternIntegrationPhMCandidate：CHENXingPhMSupervis

2、oroGUANHong—quan，ProfessorAbstractObjective：ToinvestigatetheeffectsofShufengDecoctionontheriseincapi1larypermeabi1ity’’the‘caused’。。staminemdaplpermeablo：tthemlcecausedbyh1stamlneanconducttheexperimentalstudybyusingrats’

3、sensitizationanimalmodeloftypelhypersensltlvltyandthusdlscusstheettectsand一一一t一●●●■o●■^，’‘一～^一’’■oT。一。JmechanismofShufengDecoctlonreslstlngtype上hypersensltlVlty，Provldlngtheoretlcevldenceforthec上1nlcatappllcatlonofbhufen

4、g●一一●‘一‘1‘‘’●一一一DecoctiontotreatingacuteurticariaMethods：TodeterminetheeffectsandmechanismofShufengDecoctionon‘●●●1—■一’一■’?！痶her1se1ncapl上IaryPermeabl11tyofthemlcecausedbyhistamlnethroughtheuseofspectrophotometer；sensiti

5、zationanimalmodeisoftypeIhypersensitivitywereinducedbyOVATodeterminetheeffectofShufengDecoctiononthecontentofIFN—Y、IL一4andIgEinserumoftheratsingroupbyELISAResults：ShufengDecoctionhasinhibitingfunctionoftheriseincapillary

6、permeabilityofthemicecausedbyhistamine(PO01)，‘‘●‘●’●●n’r’i■butthe1nhlbltlng士unctlonsotthelow、hlgh—dosegroupsareinferiortothechlorpheniraminegroup，thereisremarkable‘o，’，’T111’d1士士erencebetweenhlgn—dosegroupandch上orphenlra

7、mlnegroup(PO01)ShufengDecoctioncanincreasethecontentofIFN—Yintherats’serumofsensitizationanimalmodeloftypeIhypersensitivity，thereareremarkabledifferencesofmakingcomparisonbetweenShufengDecoctiongroupandmodelgroup(PO05)：S

8、hufengDecoctioncandecreasethecontentofIL一4andIgEintherats’serumofsensitizationanimalmodeloftypeIhypersensitivity，therearebothremarkabledifferencesofmakingcomparisonbetweenShufengDecoctiongroupandmodelgroup(PO01)，andthere